Susanne M. Rafelski
Susanne M. Rafelski
Mission statement
Multi-scale Analysis of Principles of Cellular Organization
My long-term objective is to understand the spatial and dynamic organization of the cell at all levels of complexity:
-How are processes at the molecular level integrated to generate subcellular structures?
- How are the size, shape, and interactions of these structures controlled at the systems level to respond to the needs of the cell?
- How does improper internal organization contribute to the cellular basis of disease?
As a model system for intracellular organization I study the size and topology of mitochondrial networks in budding yeast.
I take an interdisciplinary approach by combining microscopy, molecular genetics, and computational methods.